CAS Name: (17b)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
Methandrostenolone is a 17-alpha-alkylated oral anabolic-androgenic steroid with
anabolic properties that are more pronounced than its androgenic effects. It has
little progestational activity and easily converts to estrogens. Methandrostenolone
has an anabolic activity index 0.60 and an androgenic activity index 0.20. Methandrostenolone
has an extra double bond in the A-ring and, therefore, is not converted by 5-alpha
reduction into DHT. Since methandrostenolone was created in the 1960s, it
has been used for many different applications.
At present, the only legitimate therapeutic indications for this anabolic steroid
are: replacement of male sex steroids in men who have androgen deficiency, for example
as a result of loss of both testes; the treatment of certain rare forms of aplastic
anemia which are or may be responsive to anabolic androgens; and, in certain countries,
to counteract catabolic states, for example after major trauma.
Packing: 100 tablets in a Glass Vial
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- Dosage and administrationDosage and administration
The daily adult dosage is 10-50 mg.
- Adverse reactionsAdverse reactions
Virilization in women; prostatic hypertrophy, impotence and azoospermia in men;
acne, abnormal lipids. Fluid and electrolyte disturbances: sodium and water retention
can occur and result in edema; hypercalcemia is also reported. Insulin resistance
with a fall in glucose tolerance.
Known or suspected carcinoma of the prostate or the male breast.
Pregnancy, because of possible masculinization of the fetus. Nephrosis, the nephrotic
phase of nephritis, hypercalcemia, polycythemia.